Elizaveta Trukhina/Nikolay Lysakov (Irkutsk, RUS) qualified for the 2021 Russian Mixed Doubles Cup playoffs, dropping their quarterfinals match 6-4 against Anastasia Babarykina/Konstantin Manasevich (Saint-Petersburg, RUS). of the 2021 Russian Mixed Doubles Cup in Irkutsk, Russia;
 
Trukhina/Lysakov finished 4-0 in the 20-team qualifying round. . In their opening game, Trukhina/Lysakov defeated Julia Kuznetsova/Vladislav Velichko (Krasnoyarsk, RUS) 12-8, then won 6-2 against Valeria Denisenko/Kirill Palagney (Irkutsk, RUS) and 13-0 against Daria Semenova/Vasiliy Telezhkin (Yaroslav, RUS). Trukhina/Lysakov won 6-2 against Aleksandra Kardapoltseva/Petr Kuznetsov (Dmitrov, RUS) in their final qualifying round match.
 
Trukhina/Lysakov ranks 256th overall on the Year-to-Date rankings with 0.000 points earned so far this season.